2-Chloroethyl 2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)acetate
نویسندگان
چکیده
The mol-ecular packing of the title compound, C(17)H(17)Cl(2)NO(2)S, is stabilized by weak C-H⋯O and C-H⋯Cl inter-actions. The ester chain is almost planar with a mean deviation of 0.0605 Å and makes dihedral angles of 71.60 (4) and 74.70 (8)° with the benzene ring and the thio-phene ring, respectively. The benzene and thio-phene rings make a dihedral angle of 84.22 (7)°.
منابع مشابه
3-Bromopropyl 2-(2-chlorophenyl)-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)acetate
In the crystal structure of the title compound, C(18)H(19)BrClNO(2)S, weak C-H⋯O inter-actions help to establish the packing.
متن کامل2-Chloro-1-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)ethanone
In the title compound, C(9)H(10)ClNOS, the dihedral angle between the planar thio-phene ring and 2-chloro-ethane moiety (r.m.s deviations of 0.003 and 0.015 Å, respectively) is 45.79 (6)°. The tetra-hydro-pyridine ring adopts a half-chair conformation. The crystal packing reveals inter-molecular C-H⋯O inter-actions.
متن کامل5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
In the title compound, C(16)H(16)ClNO(2)S, the benzene and thio-phene rings make a dihedral angle of 72.60 (4)°. In the crystal, weak C-H⋯O inter-actions are observed.
متن کامل5-(2-Cyanobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
In the title mol-ecule, C17H16N2O2S, the tetra-hydro-pyridine ring exhibits a half-chair conformation. The mean planes of the ester chain and benzene ring are twisted by 5.5 (1) and 81.32 (5)°, respectively, from the plane of thio-phene ring. In the crystal, weak C-H⋯O inter-actions link mol-ecules related by translation along [100] into chains.
متن کاملPrasugrel, a new medicine for preventing blockages in the arteries
Prasugrel {systematic name: 5-[(2-cyclo-propyl-carbon-yl)(2-fluoro-phen-yl)meth-yl]-4,5,6,7-tetra-hydro-thieno[3,2-c]pyridin-2-yl acetate}, C(20)H(20)FNO(3)S, is a new third-generation thienopyridine which was recently approved for clinical use as a more potent blocker of the platelet P2Y(12) receptor than clopidogrel, which was previously used for this purpose. The mol-ecule features a tetra-h...
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عنوان ژورنال:
دوره 66 شماره
صفحات -
تاریخ انتشار 2010